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Top 5 research news stories from Beyond Celiac in 2024

January 15, 2025
Many computer arrows pointing at a green box with a question mark on it.

In the digital age, it’s easy for information to get lost in the flood of a feed. To catch you up to speed, we’re sharing the top celiac disease research stories of 2024, based on visits from community members like you. If any of the stories sound interesting, be sure to click the link and read the article in full!

5. The connection between celiac disease and obesity explored at DDW

Summary: Obesity was more common in those with celiac disease compared to those without celiac disease, analysis of a large national database of health information found.

This is particularly compelling research because celiac disease was historically associated with thin, underweight patients, which led to the erroneous belief that people who were overweight could not have celiac disease. This study suggests the truth is more complex.

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4. Special issue of AGA journal highlights progress in celiac disease

Summary: Beyond Celiac and the American Gastroenterological Associate partnered to bring important updates in celiac disease research, management and more to patients through patient-friendly summaries of recent articles published by AGA.

The AGA, in an effort to make research more accessible to patients, tapped our very own Amy Ratner, Beyond Celiac director of scientific affairs, to write summaries of the topics covered in the special issue, including the impact the first drug that gets approved to treat celiac disease will have on disease diagnosis and management, the way celiac disease affects the body beyond the gut, and the broad economic burden of celiac disease.

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3. Multiple courses of antibiotics may play role in celiac disease development for at-risk children, study finds

Summary: If a child at risk for celiac disease is prescribed antibiotics multiple times, it may increase the chance that celiac disease will develop, according to a new study. Antibiotics were tied to an increase in a protein that loosens the connection between cells in the intestine. In the future, tests for that protein might be used to determine who is likely to develop celiac disease.

It is extremely important to note that “The study did not recommend avoiding antibiotics prescribed for bacterial infections, as these are necessary treatments.”

The findings from this study are intriguing, but it’s important to be specific and nuanced when discussing this topic. So if there is any article from this list that you read in full, let it be this one.

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2. New results from clinical trial shows continued progress for a drug to treat celiac disease

Summary: Increased doses of a drug being studied for the treatment of celiac disease tempered the response to gluten in celiac disease patients and remained as safe and well tolerated as lower doses.

Our audience was, as in years prior, interested in any updates on the search for treatments and a cure for celiac disease. The Beyond Celiac team is happy to continue providing that information!

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1. Potential Drug to Treat Celiac Disease Prevents Damage Caused by Gluten in Recent Study of Molecular Action

Summary: A new study that analyzed the activity of more than 10,000 genes found that a drug being investigated to treat celiac disease prevented intestinal damage caused by gluten.

As in years past, our top story was about promising drug trial results. While we will continue to write in-depth updates as we learn more information, you can also track general progress of each drug currently being considered on our drug development pipeline page.

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